NADH stands for “nicotinamide adenine dinucleotide (NAD) + hydrogen (H).” This chemical occurs naturally in the body and plays a role in the chemical process that generates energy. People use NADH supplements as medicine.
NADH is a crucial coenzyme in making ATP. … Now, we have the reduced form, or NADH. The molecule acts as a shuttle for electrons during cellular respiration. At various chemical reactions, the Is NADH a vitamin?
NADH, known as nicotinamide adenine dinucleotide, is a coenzyme, partly made from nicotinamide (vitamin B3). NADH, through a series of reactions with acetyl and oxygen, is able to produce energy. … Therefore, a good supply optimizes energy production in the body.
NAD+ picks up an electron from glucose, at which point it becomes NADH.
The difference between NAD+ and NADH?
NAD+ is the oxidized (burned) coenzyme form of vitamin B3. NAD and NADH are converted into each other in numerous different metabolic activities. In some metabolic reactions, it is NAD which is the needed catalyst, with NADH a useful by-product; in other reactions the situation is reversed.
NAD and NADH also serve to activate various enzymes. NADH is the first of five enzyme complexes of the electron transport chain where much of the ATP bioenergy that runs every biological process of the body is formed.
NADH is necessary to oxidize all foodstuffs (fats, sugars, amino acids) into ATP bioenergy. As all living cells require energy to survive, NADH reacts with oxygen to form water and energy. One molecule of NADH yields three molecules of ATP (the stored form of energy), with the amount of NADH present dictating the amount of energy produced. The heart muscle cells contain 90mcg of NADH per gram of tissue, with brain and muscle tissue containing 50mcg per gram. Even red blood cells contain NADH with 4mcg per gram. The more NADH present in cells, theoretically, the more efficient they function in energy production.
NADH was never really considered as an oral dietary supplement due to its high reactivity and probable degradation in the blood. However, a stable, disodium salt oral form of NADH has been introduced and used clinically with reported effectiveness.
Active Forms
B-nicotinamide adenine dinucleotide; disodium salt form.
Absorption
NAHD is readily absorbed from the intestinal tract.
Toxicities & Precautions
General
NADH is generally considered to be safe in recommended dosages.
Functions In The Body
Cellular energy production – involved in ATP production via oxidative phosphorylation.
Cell regulation and DNA repair – genetic codes may become damaged by various toxins and environmental stresses such as radiation, UV light, ozone, and chemical toxins (including certain pharmaceutical drugs).
Enhances cellular immunity – useful in Chronic Fatigue Syndrome and in athletes.
Antioxidant – protects cells against free radical damage.
Stimulator of dopamine, norepinephrine, and other catecholamine production – stimulatory effects, potentially increasing athletic performance and of benefit in Parkinson’s, Alzheimer ’s disease, and Chronic Fatigue Syndrome.
Clinical Applications
Alzheimer’s Disease
Chronic Fatigue Syndrome
Depression
Jet Lag
Parkinson’s Disease.
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